🧬 Protein Interaction Conservation Explorer

Systematic identification of conserved residue interaction fingerprints across 2460 protein families | 654511 conserved interactions

Total Families

2460
with qualifying conserved interactions

Total Interactions

654511
passing all conservation thresholds

Extreme (≥90%)

67817
PDBCon ≥ 0.90

Exceptional (≥75%)

135824
PDBCon 0.75–0.89

Results by Ångström Distance

Top 25 Families by Conservation

RankFamilyBest PDBConInteractionsPerfectAvg Å
1 64660
100.0%
 34293736.61
2 88799
100.0%
 331126.38
3 48109
100.0%
 24684206.24
4 52022
100.0%
 24684206.24
5 52336
100.0%
 24684206.24
6 232790
100.0%
 2406416.24
7 232765
100.0%
 23621676.25
8 64618
100.0%
 2360386.35
9 254211
100.0%
 2136896.25
10 47695
100.0%
 20772076.13
11 48480
100.0%
 20772076.13
12 57818
100.0%
 20772076.13
13 81405
100.0%
 20772076.13
14 81410
100.0%
 20772076.13
15 81414
100.0%
 20772076.13
16 81418
100.0%
 20772076.13
17 81422
100.0%
 20772076.13
18 81426
100.0%
 20772076.13
19 81430
100.0%
 20772076.13
20 103502
100.0%
 19945566.13
21 81451
100.0%
 192746.10
22 64576
100.0%
 190086.09
23 254197
100.0%
 1879266.10
24 64311
100.0%
 182616.08
25 53037
100.0%
 181056.06

Most Conserved Fingerprints

RankFingerprintTranslationFamiliesBest PDBCon
1 000001000000000011LEU(1)-ILE(1)-VAL(1)1769
100.0%
2 000002000000000010LEU(2)-ILE(1)1548
100.0%
3 000002000000000001LEU(2)-VAL(1)1445
100.0%
4 100001000000000001PHE(1)-LEU(1)-VAL(1)1364
100.0%
5 100001000000000010PHE(1)-LEU(1)-ILE(1)1314
100.0%
6 000001000000000002LEU(1)-VAL(2)1275
100.0%
7 000001000000000020LEU(1)-ILE(2)1244
100.0%
8 100002000000000000PHE(1)-LEU(2)1089
100.0%
9 000002000000000011LEU(2)-ILE(1)-VAL(1)1017
100.0%
10 100000000000000011PHE(1)-ILE(1)-VAL(1)998
100.0%
11 000000000000000012ILE(1)-VAL(2)980
100.0%
12 000001010100000000LEU(1)-ARG(1)-GLU(1)963
100.0%
13 000000000000000021ILE(2)-VAL(1)922
100.0%
14 000000101100000000LYS(1)-ASP(1)-GLU(1)895
100.0%
15 000003000000000000LEU(3)876
100.0%
16 100001000000000011PHE(1)-LEU(1)-ILE(1)-VAL(1)860
100.0%
17 000000110100000000LYS(1)-ARG(1)-GLU(1)825
100.0%
18 010000100100000000TYR(1)-LYS(1)-GLU(1)821
100.0%
19 000000101000100000LYS(1)-ASP(1)-SER(1)820
100.0%
20 000001000000000021LEU(1)-ILE(2)-VAL(1)819
100.0%
21 000001000000000012LEU(1)-ILE(1)-VAL(2)807
100.0%
22 000001100100000000LEU(1)-LYS(1)-GLU(1)792
100.0%
23 000000001000110000ASP(1)-SER(1)-THR(1)763
100.0%
24 000000011100000000ARG(1)-ASP(1)-GLU(1)756
100.0%
25 000000101000010000LYS(1)-ASP(1)-THR(1)751
100.0%

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Protein Family Interaction Conservation Analysis — Powered by Delaunay Triangulation & SCOPe